Which of the following would be appropriate for treating sensitive skin with inflamed acne?

Mandelic serum is particularly suitable for treating sensitive skin with inflamed acne due to its gentle nature compared to other acids. It is derived from almonds and has a larger molecular size, which allows for slower penetration into the skin. This characteristic makes it less irritating, making it a better choice for sensitive skin types. Additionally, mandelic acid possesses anti-inflammatory and antibacterial properties that can help calm inflamed acne lesions while promoting gentle exfoliation and improving skin texture without causing excessive irritation.

In contrast, high percentage glycolic acid may be too harsh for sensitive skin, as it can lead to increased irritation and inflammation. Salicylic acid, while effective for acne treatment due to its ability to penetrate pores and exfoliate, can also be irritating for those with highly sensitive skin. Over-the-counter benzoyl peroxide is a powerful antibacterial agent that can effectively target acne, but it may also cause dryness and irritation, particularly in sensitive skin types. Thus, mandelic serum stands out as the most appropriate option for this specific skin concern.